Description

2-Methyl-3-(Trifluoromethyl)Bromobenzene is a high-purity, multi-functional halogenated aromatic building block essential for advanced organic synthesis. Its unique structure, featuring both a bromine substituent and a trifluoromethyl group, makes it a critical intermediate for introducing specific functionalities into target molecules. This compound is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and material science industries for constructing complex chemical architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring trifluoromethylated aromatic cores for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the trifluoromethyl group improves product efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of advanced organic electronic materials, liquid crystals, and polymers with tailored properties.
• Cross-Coupling Reactions: Acts as a versatile electrophile in Suzuki, Stille, and Negishi couplings to form biaryl structures.
• Functional Group Transformation: The bromine atom allows for further functionalization via metal-halogen exchange or nucleophilic substitution.

Basic Information

Product Name	2-Methyl-3-(Trifluoromethyl)Bromobenzene
CAS No.	69902-83-6
Molecular Formula	C8H6BrF3
Molecular Weight	239.04 g/mol
Synonyms	1-Bromo-2-methyl-3-(trifluoromethyl)benzene; 3-Bromo-2-methylbenzotrifluoride; 2-Methyl-α,α,α-trifluoro-m-bromotoluene; m-Bromo-o-methylbenzotrifluoride; 2-Methyl-3-trifluoromethylphenyl bromide; 3-(Trifluoromethyl)-2-methylbromobenzene; 2-Methyl-3-(trifluoromethyl)phenyl bromide
EINECS	Contact for details

Quality Control

Our 2-Methyl-3-(Trifluoromethyl)Bromobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and powerful oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Total impurities ≤ 2.0%
Density	~1.6 g/cm³
Refractive Index	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.