Description

n-(6-Aminohexyl)-5-Chloro-2-Naphthalenesulfonamide Hydrochloride is a specialized organic compound that serves as a critical building block and research chemical in advanced life science applications. Its value lies in its unique molecular structure, which combines a naphthalene sulfonamide core with a functionalized aminohexyl side chain, making it a versatile intermediate for probe and inhibitor synthesis. This product is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those developing enzyme inhibitors, fluorescent probes, and targeted molecular therapeutics.

Application

• Pharmaceutical Intermediate: Key synthetic precursor for the development of novel enzyme inhibitors and receptor antagonists.
• Biochemical Research: Used as a scaffold or building block in the synthesis of fluorescent probes and activity-based protein profiling (ABPP) reagents.
• Protease Inhibitor Development: The sulfonamide group is a common pharmacophore in the design of inhibitors for various protease targets.
• Chemical Biology Tool: Utilized in the study of protein-ligand interactions and cellular signaling pathways due to its modifiable functional groups.
• High-Purity Reference Standard: Serves as an analytical standard for quality control and method development in regulatory and research laboratories.

Basic Information

Product Name	n-(6-Aminohexyl)-5-Chloro-2-Naphthalenesulfonamide Hydrochloride
CAS No.	69762-85-2
Molecular Formula	C₁₆H₂₁ClN₂O₂S • HCl
Molecular Weight	377.33 g/mol
Synonyms	5-Chloro-N-(6-aminohexyl)-2-naphthalenesulfonamide hydrochloride; W-7 hydrochloride; N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide hydrochloride; Calmodulin antagonist W-7 hydrochloride; 1-(5-Chloro-1-naphthalenesulfonyl)hexamethylenediamine hydrochloride
EINECS	Contact for details

Quality Control

Our n-(6-Aminohexyl)-5-Chloro-2-Naphthalenesulfonamide Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.