Description

(R)-Butaprost CAS NO 69648-38-0 is a high-purity, single-enantiomer prostaglandin analog. This compound is a critical chiral intermediate and active pharmaceutical ingredient (API) used in advanced pharmaceutical research and development. It is primarily utilized by pharmaceutical companies and research institutions focused on developing novel therapeutics, particularly in the areas of ophthalmology and cardiovascular medicine.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of prostaglandin-based APIs.
• Ophthalmic Drug Development: Used in research for glaucoma and ocular hypertension treatments due to its intraocular pressure-lowering activity.
• Cardiovascular Research: Investigated for its vasodilatory and antiplatelet aggregation properties in preclinical studies.
• Biochemical Research: Employed as a standard or reference compound in pharmacological assays and receptor binding studies.
• Process Chemistry: Utilized in the development and scale-up of stereoselective synthetic routes.

Basic Information

Product Name	(R)-Butaprost
CAS No.	69648-38-0
Molecular Formula	C23H38O5
Molecular Weight	394.55 g/mol
Synonyms	(R)-Butaprost; (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-4-phenoxy-1-buten-1-yl]cyclopentyl]-5-Heptenoic Acid; 9-Oxo-11α,15α-dihydroxy-17-phenyl-18,19,20-trinorprosta-5Z,13E-dien-1-oic Acid (R-isomer); TR-4979; Prostaglandin F2α analog (R); UNII-1W3P6B2V8I
EINECS	Contact for details

Quality Control

Our (R)-Butaprost is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to prevent oxidation and degradation. The product is light-sensitive and easily oxidized.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (R-isomer)
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.