Description

(11α,13E,16R)-1,11,16-Trihydroxy-17,17-Dimethylprost-13-En-9-One is a high-purity synthetic prostaglandin analog, a critical intermediate in advanced pharmaceutical research and development. Its value lies in its precise stereochemistry and functional groups, which are essential for synthesizing novel therapeutic agents targeting specific biological pathways. This compound is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new drugs in areas such as ophthalmology, dermatology, and inflammation.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel prostaglandin-based drug candidates.
• Ophthalmic Drug Research: Used in the development of next-generation treatments for glaucoma and ocular hypertension.
• Dermatological Formulations: Serves as a precursor for active pharmaceutical ingredients (APIs) in skincare and wound-healing applications.
• Inflammation & Pain Management Studies: Employed in preclinical research to create analogs for modulating inflammatory responses.
• Chemical Biology Probes: Utilized to study prostaglandin receptor interactions and signaling pathways.
• Process Chemistry & Scale-Up: Acts as a reference standard and starting material for process optimization and GMP manufacturing.

Basic Information

Product Name	(11α,13E,16R)-1,11,16-Trihydroxy-17,17-Dimethylprost-13-En-9-One
CAS No.	69648-08-4
Molecular Formula	C22H38O5
Molecular Weight	382.54 g/mol
Synonyms	16R-17,17-Dimethylprostaglandin E1; Travoprost Impurity; 16R-Travoprost Related Compound; 17,17-Dimethyl-PGE1; (11α,13E,16R)-1,11,16-Trihydroxy-17,17-dimethylprost-13-en-9-one; 9-Oxo-11α,16R-dihydroxy-17,17-dimethylprosta-13E-en-1-oic acid derivative; AL 6221
EINECS	Contact for details

Quality Control

Our (11α,13E,16R)-1,11,16-Trihydroxy-17,17-Dimethylprost-13-En-9-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation and degradation. Keep the container in a dry, cool, and well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.