Description

Carbaprostacyclin Methyl Ester is a stable, synthetic analog of prostacyclin (PGI2), a potent vasodilator and inhibitor of platelet aggregation. This compound is a critical intermediate and research tool for developing novel therapeutic agents targeting cardiovascular and pulmonary diseases. It is essential for pharmaceutical R&D, particularly in the synthesis of stable prostacyclin analogs for clinical studies and advanced material science applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of stable prostacyclin (PGI2) analogs for cardiovascular and pulmonary hypertension therapies.
• Biochemical Research: Used as a reference standard and active agent in studies of platelet aggregation, vasodilation, and vascular smooth muscle cell function.
• Drug Discovery & Development: Serves as a core scaffold for medicinal chemistry programs aimed at creating new IP-protected compounds with improved metabolic stability.
• Cell Culture & In Vitro Studies: Applied in laboratory settings to investigate the role of the prostacyclin pathway in various disease models.
• Material Science: Investigated for potential use in developing bioactive coatings for medical devices, such as stents, to improve hemocompatibility.

Basic Information

Product Name	Carbaprostacyclin Methyl Ester
CAS No.	69552-55-2
Molecular Formula	C₂₃H₃₈O₅
Molecular Weight	394.55 g/mol
Synonyms	Carbacyclin Methyl Ester; 5,6-Dihydro-6a-carba-PGI₂ Methyl Ester; 6a-Carbaprostacyclin Methyl Ester; Methyl (1R,2R,3aS,8bS)-1-[(E,3S)-3-hydroxyoct-1-en-1-yl]-2-[(1S,4S,5S)-5-hydroxy-7-oxabicyclo[2.2.1]heptan-2-ylidene]-2,3,3a,8b-tetrahydro-1H-cyclopenta[b]benzofuran-5-carboxylate; 6β-PGI₁ Methyl Ester; Carbaprost Methyl Ester (prostacyclin analog)
EINECS	Contact for details

Quality Control

Our Carbaprostacyclin Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. The product is hygroscopic (moisture-sensitive) and light-sensitive; allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.