Description

Carbacyclin is a stable, synthetic analog of prostacyclin (PGI₂), a potent vasodilator and inhibitor of platelet aggregation. This compound is of significant value for research and development in cardiovascular pharmacology and vascular biology. It is primarily utilized by pharmaceutical researchers, academic institutions, and R&D laboratories focused on studying thrombosis, hypertension, and endothelial cell function.

Application

• Cardiovascular Research: Used as a reference standard and active agent in studies investigating platelet aggregation, vasodilation, and vascular tone.
• Pharmacological Studies: Serves as a key tool compound for exploring prostacyclin receptor (IP receptor) signaling pathways and developing novel therapeutics.
• Biochemical Assay Development: Employed in the calibration and validation of in vitro assays designed to measure antiplatelet or vasodilatory activity.
• Cell Culture & Physiology: Applied in experimental models to study the protective effects of prostacyclin analogs on endothelial cells and vascular smooth muscle.
• Reference Standard: Provides a high-purity benchmark for analytical methods such as HPLC and LC-MS in quality control and metabolic studies.

Basic Information

Product Name	Carbacyclin
CAS No.	69552-46-1
Molecular Formula	C₂₀H₃₂O₄
Molecular Weight	336.47 g/mol
Synonyms	Carbacyclin; 5,6,7-Trinor-4,8-inter-m-phenylene-3-hydroxy-9a-homo-9-oxoprosta-4,13-dien-1-oic acid; 9a-Homo-9-oxoprosta-4,13-dien-1-oic acid, 5,6,7-trinor-4,8-inter-m-phenylene-3-hydroxy-; ZK 36374; Cicaprost; Stable prostacyclin analog
EINECS	Contact for details

Quality Control

Our Carbacyclin is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by HPLC. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.