Description

Oleandrin,Anhydro-16-Deacetyl- CAS NO 69549-58-2 is a specialized cardiac glycoside derivative, structurally related to oleandrin. This compound matters as a high-purity reference standard and key intermediate for advanced pharmaceutical research and development. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and academic sectors for applications in cardiac pharmacology, toxicology studies, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quality control and analytical method development of cardiac glycoside-based drugs.
• Biochemical Research: Serves as a critical tool in pharmacological studies to investigate Na+/K+-ATPase inhibition and its effects on cellular signaling pathways.
• Active Pharmaceutical Ingredient (API) Intermediate: Acts as a key synthetic precursor in the manufacture of specialized cardiac therapeutics and novel drug candidates.
• Toxicology and Safety Assessment: Employed in forensic and clinical toxicology labs for the identification and quantification of oleander-derived compounds.
• Academic Research: Utilized in university and institutional labs for studies in natural product chemistry, medicinal chemistry, and molecular biology.

Basic Information

Product Name	Oleandrin,Anhydro-16-Deacetyl-
CAS No.	69549-58-2
Molecular Formula	C30H46O7
Molecular Weight	518.69 g/mol
Synonyms	16-Deacetyl-16-anhydrooleandrin; Anhydro-16-deacetyloleandrin; 16-Anhydro-16-deacetyloleandrin; 3β-[(O-2,6-Dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-14-hydroxy-19-oxo-5β-card-20(22)-enolide; 16-Dehydro-16-deacetyloleandrin; Oleandrigenin 3-O-β-oleandrosyl-(1→4)-β-oleandrosyl-(1→4)-β-digitoxoside
EINECS	Contact for details

Quality Control

Our Oleandrin,Anhydro-16-Deacetyl- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates and reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.