Description

13,14-Dihydroxy-15-Ketoprostaglandin F2Alpha is a key prostaglandin metabolite and a potent bioactive lipid mediator. This compound is essential for researchers in pharmacology and biochemistry studying eicosanoid signaling pathways, inflammation, and cellular regulation. It is primarily used by pharmaceutical R&D teams, contract research organizations (CROs), and academic institutions for use as a high-purity reference standard and critical intermediate in analytical and synthetic applications.

Application

• Pharmaceutical Reference Standard: Used for the calibration of analytical instruments (HPLC, LC-MS) and the qualification of assays in drug development and metabolic studies.
• Biochemical Research: Serves as a crucial tool for investigating the role of prostaglandin metabolites in inflammatory pathways, oxidative stress, and receptor binding studies.
• Metabolite Analysis: Acts as a definitive standard for the quantification of prostaglandin F2α metabolites in biological samples such as plasma, urine, and tissue homogenates.
• Synthetic Intermediate: Employed in the organic synthesis of more complex prostaglandin analogs and derivatives for therapeutic exploration.
• Diagnostic Development: Utilized in the development and validation of diagnostic kits and immunoassays targeting specific eicosanoid pathways.

Basic Information

Product Name	13,14-Dihydroxy-15-Ketoprostaglandin F2Alpha
CAS No.	69536-60-3
Molecular Formula	C₂₀H₃₂O₇
Molecular Weight	384.47 g/mol
Synonyms	15-Keto-13,14-dihydro-PGF2α; 15-Keto-dihydro-PGF2α; 13,14-Dihydro-15-keto-prostaglandin F2α; PGF2α metabolite; 9α,11α,15-Trihydroxy-13,14-dihydro-2,3,4,5,20-pentanor-19-carboprost-5-en-1-oic acid; 15-Keto-13,14-dihydroprostaglandin F2α; 15-KDH PGF2α
EINECS	Contact for details

Quality Control

Our 13,14-Dihydroxy-15-Ketoprostaglandin F2Alpha is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for research and development. A detailed Certificate of Analysis (COA) providing batch-specific data is supplied with every order.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The material is hygroscopic and must be kept in a dry environment. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.