Description

2-Cyanobenzenesulphonyl Chloride is a versatile and highly reactive aromatic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its dual functionality, where the sulfonyl chloride group acts as an excellent electrophile for sulfonamide formation, and the cyano group offers a handle for further transformations into carboxylic acids, amides, or heterocycles. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and fine chemicals with specific biological activities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drugs, including enzyme inhibitors, receptor antagonists, and antimicrobial agents.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides with tailored properties.
• Dye and Pigment Manufacturing: Used in the production of specialty dyes and organic pigments, leveraging the aromatic sulfonyl chloride moiety.
• Polymer Chemistry: Monomer or modifier for creating specialty polymers with specific functional groups, such as polyamides or polyesters derived from the cyano group.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry in exploring new synthetic routes and compound libraries.
• Ligand and Catalyst Preparation: Intermediate for synthesizing complex ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Cyanobenzenesulphonyl Chloride
CAS No.	69360-26-5
Molecular Formula	C7H4ClNO2S
Molecular Weight	201.63 g/mol
Synonyms	2-Cyanobenzenesulfonyl chloride; o-Cyanobenzenesulfonyl chloride; Benzenesulfonyl chloride, 2-cyano-; 2-Cyanophenylsulfonyl chloride; NSC 403796; 2-Cyano-benzenesulfonyl chloride; 2-Cyanobenzene-1-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Cyanobenzenesulphonyl Chloride is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, IR for structural confirmation, and Karl Fischer titration for moisture content. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.