Description

5-Bromo-2-Methylbenzenesulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to act as a sulfonylation reagent, facilitating the introduction of the sulfonyl functional group to create compounds with tailored properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drugs, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and pesticides with enhanced efficacy.
• Material Science: Building block for creating specialty polymers, dyes, and liquid crystals.
• Chemical Research: A valuable reagent in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Peptide Modification: Employed to modify amino acid side chains or protect functional groups during peptide synthesis.

Basic Information

Product Name	5-Bromo-2-Methylbenzenesulfonyl Chloride
CAS No.	69321-56-8
Molecular Formula	C7H6BrClO2S
Molecular Weight	269.54 g/mol
Synonyms	2-Methyl-5-bromobenzenesulfonyl chloride; 5-Bromo-o-toluenesulfonyl chloride; 5-Bromo-2-toluenesulfonyl chloride; 1-Bromo-4-methyl-3-sulfonylchloridobenzene; 2-Methyl-5-bromophenylsulfonyl chloride; 5-Bromo-2-methylphenylsulfonyl chloride; Benzenesulfonyl chloride, 5-bromo-2-methyl-
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Methylbenzenesulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.