Description

n-Acetyldoxorubicn is a chemically modified derivative of the potent anthracycline antibiotic, doxorubicin. This compound is of significant interest in pharmaceutical research and development, particularly for its potential to alter pharmacokinetic properties and modulate biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel chemotherapeutic agents and the study of structure-activity relationships.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of novel doxorubicin analogs and prodrugs for cancer therapy research.
• Biochemical Research: Used as a reference standard or experimental compound in studies investigating the mechanism of action, resistance, and toxicity profiles of anthracycline drugs.
• Antitumor Agent Development: Serves as a precursor for developing modified chemotherapeutic agents with potentially improved efficacy or reduced side effects.
• Academic Research: Employed in university and institutional labs for fundamental research in medicinal chemistry and oncology.

Basic Information

Product Name	n-Acetyldoxorubicn
CAS No.	69299-74-7
Molecular Formula	C₂₇H₂₉NO₁₁
Molecular Weight	543.52 g/mol
Synonyms	N-Acetyldoxorubicin; 14-O-Acetyldoxorubicin; Doxorubicin 14-acetate; AD 32; (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-glycoloyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione 14-acetate
EINECS	Contact for details

Quality Control

Our n-Acetyldoxorubicn is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A Certificate of Analysis (COA) detailing specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.