Description

4-(2-Methoxyethoxy)-3-Methylbenzene-1-Sulfonyl Chloride is a specialized aromatic sulfonyl chloride derivative, a key reactive intermediate in advanced organic synthesis. Its value lies in its dual functionality, where the sulfonyl chloride group serves as a versatile electrophile for forming sulfonamides and sulfonate esters, while the alkoxy side chain offers solubility and tunable electronic properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel sulfonamide-based drug candidates, including potential enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the sulfonamide moiety is a key pharmacophore.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of specialty polymers and functional materials.
• Dye and Pigment Manufacturing: Serves as an intermediate for synthesizing sulfonated dyes and colorants with enhanced solubility and fastness properties.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry research, enabling structure-activity relationship (SAR) studies.
• Liquid Crystal and Electronic Materials: Potential use in the synthesis of organic semiconductors and liquid crystal compounds due to its aromatic and ether-containing structure.

Basic Information

Product Name	4-(2-Methoxyethoxy)-3-Methylbenzene-1-Sulfonyl Chloride
CAS No.	69129-46-0
Molecular Formula	C10H13ClO4S
Molecular Weight	264.73 g/mol
Synonyms	3-Methyl-4-(2-methoxyethoxy)benzenesulfonyl chloride; 1-(2-Methoxyethoxy)-2-methyl-4-sulfonylchloridobenzene; 4-(2-Methoxyethoxy)-3-methylbenzenesulfonyl chloride; 2-Methyl-5-sulfonylchlorido-1-(2-methoxyethoxy)benzene; 69129-46-0; 3-Methyl-4-(β-methoxyethoxy)benzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4-(2-Methoxyethoxy)-3-Methylbenzene-1-Sulfonyl Chloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and Karl Fischer titration for moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.