Description

3-tert-Butyl-4-Methoxy-Benzenesulfonyl Chloride is a specialized sulfonyl chloride derivative, a key reactive intermediate in advanced organic synthesis. This compound is valued for its role in introducing the sulfonyl functional group, enabling the construction of complex molecules with tailored properties. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as sulfonamide formation and material science research.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators that require specific sulfonyl group chemistry.
• Material Science Research: Employed in the development of specialty polymers, dyes, and photoactive materials where the sulfonyl moiety modifies physical or electronic properties.
• Chemical Biology Probes: Serves as a reagent for labeling proteins or modifying biomolecules to study biological pathways and interactions.
• Cross-Coupling Reactions: Acts as an electrophile in palladium-catalyzed cross-coupling reactions to create biaryl sulfones.
• Ligand and Catalyst Development: Used to synthesize novel ligands and organocatalysts for asymmetric synthesis.

Basic Information

Product Name	3-tert-Butyl-4-Methoxy-Benzenesulfonyl Chloride
CAS No.	69129-42-6
Molecular Formula	C₁₁H₁₅ClO₃S
Molecular Weight	262.75 g/mol
Synonyms	4-Methoxy-3-tert-butylbenzenesulfonyl chloride; 3-(tert-Butyl)-4-methoxybenzenesulfonyl chloride; 1-(tert-Butyl)-2-methoxy-4-(chlorosulfonyl)benzene; 4-(tert-Butyl)-3-methoxybenzenesulfonyl chloride; p-Methoxy-m-tert-butylbenzenesulfonyl chloride; 3-tert-Butyl-4-methoxybenzene-1-sulfonyl chloride; 3-tert-Butyl-4-methoxyphenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 3-tert-Butyl-4-Methoxy-Benzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.