Description

2-Fluoro-5-Trifluoromethylpyridine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethyl substituents, imparts significant electronic and steric properties that are essential for developing novel compounds with enhanced biological activity and material performance. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating new active ingredients, as well as by material scientists in the electronics industry.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms improve metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science: Employed in the synthesis of functional materials, including liquid crystals, organic semiconductors, and polymers with specific electronic properties.
• Chemical Research: A versatile reagent for introducing fluorinated pyridine motifs into complex molecular architectures in academic and industrial R&D.

Basic Information

Product Name	2-Fluoro-5-Trifluoromethylpyridine
CAS No.	69045-82-5
Molecular Formula	C6H3F4N
Molecular Weight	165.09 g/mol
Synonyms	5-(Trifluoromethyl)-2-fluoropyridine; 2-Fluoro-5-(trifluoromethyl)pyridine; 2-Fluoro-α,α,α-trifluoro-picoline; Pyridine, 2-fluoro-5-(trifluoromethyl)-; 69045-82-5; 2-Fluoro-5-trifluoromethyl pyridine
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Trifluoromethylpyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.