Description

Trichostatin C CAS NO 68676-88-0 is a potent and selective histone deacetylase (HDAC) inhibitor belonging to the trichostatin family of natural products. This compound is a critical research tool for investigating epigenetic regulation, chromatin remodeling, and gene expression in cellular and molecular biology. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on oncology, neurology, and metabolic disease research.

Application

• Epigenetics Research: A fundamental tool for studying histone acetylation/deacetylation dynamics and their role in gene silencing and activation.
• Cancer Biology Studies: Used to investigate the mechanisms of HDAC inhibition on cell cycle arrest, differentiation, and apoptosis in various cancer cell lines.
• Neuroscience Research: Applied in models to understand the role of epigenetic modifications in neuronal development, synaptic plasticity, and neurodegenerative diseases.
• Biochemical Assay Development: Serves as a reference standard and active compound in high-throughput screening (HTS) assays for novel HDAC inhibitor discovery.
• Stem Cell Research: Employed to modulate the epigenetic state and influence the differentiation potential of pluripotent stem cells.
• Inflammatory Disease Models: Used to explore the epigenetic control of inflammatory pathways and cytokine production.

Basic Information

Product Name	Trichostatin C
CAS No.	68676-88-0
Molecular Formula	C17H22N2O3
Molecular Weight	302.37 g/mol
Synonyms	TSA-C; Trichostatin C (TSA-C); (2E,4E,6R)-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide; HDAC Inhibitor Trichostatin C; Antibiotic Trichostatin C
EINECS	Contact for details

Quality Control

Our Trichostatin C is produced under strict quality management systems to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the exact specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under desiccated conditions. The product is hygroscopic and light-sensitive. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.