Description

7-Oxo-15-Methylprostaglandin E1 Methyl Ester is a synthetic prostaglandin analog, a key intermediate in the research and development of advanced pharmaceutical compounds. Its modified structure offers enhanced metabolic stability and targeted biological activity, making it a valuable tool for medicinal chemistry. This high-purity intermediate is primarily utilized by research institutions and pharmaceutical manufacturers focused on developing novel therapeutics in areas such as ophthalmology, dermatology, and cardiovascular research.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel prostaglandin-based drugs for glaucoma treatment and other therapeutic areas.
• Biochemical Research: Used as a reference standard and active compound in studies investigating prostaglandin receptor activity and signaling pathways.
• Medicinal Chemistry: Serves as a core scaffold for the design and optimization of new chemical entities with improved pharmacokinetic profiles.
• Ophthalmic Drug Development: Key precursor in the production of latanoprost analogs and other intraocular pressure-lowering agents.
• Dermatological Research: Investigated for potential applications in wound healing, hair growth studies, and skin barrier function.
• Academic & Contract Research: Supplied to universities and CROs for fundamental research in lipid mediator biology and drug discovery projects.

Basic Information

Product Name	7-Oxo-15-Methylprostaglandin E1 Methyl Ester
CAS No.	68538-80-7
Molecular Formula	C23H38O6
Molecular Weight	410.55 g/mol
Synonyms	15-Methyl-7-oxoprostaglandin E1 Methyl Ester; Methyl 7-oxo-15(S)-methylprostaglandin E1; 7-Keto-15-methyl PGE1 Methyl Ester; 15-Methyl-7-oxo-PGE1 ME; (5Z)-7-Oxo-15-methyl-9,11,13-prostatrien-1-oic Acid Methyl Ester; Travoprost Intermediate; Prostaglandin E1 Derivative
EINECS	Contact for details

Quality Control

Our 7-Oxo-15-Methylprostaglandin E1 Methyl Ester is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen) at a controlled temperature of -20°C or below to prevent oxidation and ensure long-term stability. The container should be kept in a dry, well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.