Description

Bromo[8-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]-1-Octynyl]Magnesium is a highly reactive organomagnesium reagent, specifically a Grignard reagent, used for the formation of carbon-carbon bonds in advanced organic synthesis. Its core value lies in enabling the precise and efficient introduction of a protected, functionalized octynyl chain into complex molecular frameworks. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for the development of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for constructing complex molecules in the research and development of new active pharmaceutical ingredients (APIs).
• Agrochemical Manufacturing: Used in the synthesis of advanced crop protection agents and herbicides that require specific alkyne-functionalized side chains.
• Liquid Crystal & OLED Material Production: Serves as a precursor for creating functionalized organic compounds used in electronic displays and optoelectronic devices.
• Polymer & Specialty Chemical Modification: Enables the functionalization of polymers and other materials by introducing alkyne groups for further click chemistry reactions.
• Academic & Industrial R&D: A critical reagent for methodology development and exploratory synthesis in organic chemistry laboratories.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fragrance, flavor, and dye intermediates.

Basic Information

Product Name	Bromo[8-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]-1-Octynyl]Magnesium
CAS No.	68516-36-9
Molecular Formula	C₁₃H₂₁BrMgO₂
Molecular Weight	313.51 g/mol
Synonyms	8-[(Tetrahydro-2H-pyran-2-yl)oxy]-1-octynylmagnesium bromide; (8-((Tetrahydro-2H-pyran-2-yl)oxy)oct-1-yn-1-yl)magnesium bromide; THP-Protected 8-Hydroxy-1-octynylmagnesium Bromide; Grignard Reagent of 8-(Tetrahydro-2-pyranyloxy)-1-octyne; Bromo(8-((tetrahydro-2H-pyran-2-yl)oxy)oct-1-yn-1-yl)magnesium
EINECS	Contact for details

Quality Control

Our Bromo[8-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]-1-Octynyl]Magnesium is manufactured under strict quality protocols to ensure batch-to-batch consistency and high reactivity. Each lot undergoes rigorous analytical testing, including titration for Grignard concentration and spectroscopic analysis for identity and purity. Certificates of Analysis (COA) detailing specific results are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile, hygroscopic, and easily oxidized nature, this reagent must be stored under a dry, inert atmosphere (argon or nitrogen) at recommended temperatures of 2°C to 8°C. Handle and open containers only in a moisture-free environment to prevent decomposition and ensure optimal performance.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (IR)	Conforms to structure
Concentration (Titration)	0.5 M in THF or as specified
Purity (HPLC)	≥ 95% (by GC/HPLC of quenched sample)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.