Description

(2E,5E)-7-[(1R)-2β-[(E,R)-4-(3-Chlorophenoxy)-3-Hydroxy-1-Butenyl]-3α,5α-Dihydroxycyclopentan-1α-Yl]-2,5-Heptadienoic Acid Methyl Ester is a high-purity synthetic prostaglandin analog, a key intermediate in advanced pharmaceutical research and development. This compound is critical for its role in studying and developing novel therapeutic agents targeting specific physiological pathways. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of advanced prostaglandin-based drug candidates.
• Biochemical Research: Used as a reference standard or active probe in pharmacological studies to investigate receptor binding and signal transduction mechanisms.
• Process Development: Serves as a key material for optimizing synthetic routes and scaling up production of target active pharmaceutical ingredients (APIs).
• Academic Research: Employed in university and institutional labs for cutting-edge research in medicinal chemistry and organic synthesis methodologies.
• Custom Synthesis: A starting point for the contract development and manufacturing of specialized, high-value compounds for client-specific projects.

Basic Information

Product Name	(2E,5E)-7-[(1R)-2β-[(E,R)-4-(3-Chlorophenoxy)-3-Hydroxy-1-Butenyl]-3α,5α-Dihydroxycyclopentan-1α-Yl]-2,5-Heptadienoic Acid Methyl Ester
CAS No.	68399-12-2
Molecular Formula	C23H29ClO6
Molecular Weight	436.93 g/mol
Synonyms	Methyl (2E,5E)-7-[(1R,2R,3R,5S)-2-[(E,3R)-4-(3-Chlorophenoxy)-3-hydroxybut-1-en-1-yl]-3,5-dihydroxycyclopentyl]hepta-2,5-dienoate; 9-Deoxo-9a-homo-9a-methylene-16-phenoxy-tetranor PGF2α Methyl Ester (Analog); Prostaglandin F2α Analog Methyl Ester; 16-(3-Chlorophenoxy)-9-deoxo-9a,11a-didehydro-9a-homo PGF2α Methyl Ester; 68399-12-2; UNII-9VXA7B7M3B
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, typically determined by HPLC, NMR, and IR spectroscopy. We support development and cGMP-grade requirements, with specifications tailored to your project phase.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. Due to its hygroscopic nature, the container should be allowed to reach room temperature before opening to minimize moisture ingress. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.