Description

Sorbinil is a potent aldose reductase inhibitor, a key compound in advanced pharmaceutical research and development. Its primary value lies in its ability to modulate metabolic pathways, making it a critical tool for investigating diabetic complications and related biochemical mechanisms. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, well-characterized compounds for synthesis and preclinical studies.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced therapeutic agents targeting metabolic disorders.
• Biochemical Research: Used as a reference standard and active compound in studies of aldose reductase enzyme inhibition and its role in diabetic complications.
• Preclinical Development: Serves as a critical material for formulation studies, pharmacokinetic profiling, and efficacy testing in research models.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex molecules for medicinal chemistry and drug discovery programs.
• Reference Standard: Provides a high-purity benchmark for quality control and analytical method development in laboratory settings.

Basic Information

Product Name	Sorbinil
CAS No.	68367-52-2
Molecular Formula	C₁₅H₁₄N₂O₃
Molecular Weight	270.28 g/mol
Synonyms	(S)-6-Fluoro-2,3-dihydrospiro[4H-1-benzopyran-4,4'-imidazolidine]-2',5'-dione; CP-45,634; Sorbinil (USAN); Spiro[4H-1-benzopyran-4,4'-imidazolidine]-2',5'-dione, 6-fluoro-2,3-dihydro-, (4S)-; (4S)-6-Fluoro-2,3-dihydrospiro[4H-1-benzopyran-4,4'-imidazolidine]-2',5'-dione
EINECS	Contact for details

Quality Control

Our Sorbinil is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical and biotechnology partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccant use and inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.