Description

3-Bromo-4-Fluorobenzotrifluoride is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound matters because it provides a versatile trifluoromethylated, halogenated core for constructing complex molecules with tailored electronic and steric properties. It is primarily needed by R&D chemists and process engineers in the pharmaceutical and agrochemical industries for developing new active ingredients, as well as in materials science for creating specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediates: A key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a crucial building block for fluorine-containing liquid crystal compounds used in high-performance displays.
• Organic Electronics: Employed in the research and production of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create biaryl structures.
• Chemical Research & Development: A valuable reagent for exploring new fluorination methodologies and constructing complex molecular architectures in academic and industrial labs.

Basic Information

Product Name	3-Bromo-4-Fluorobenzotrifluoride
CAS No.	68322-84-9
Molecular Formula	C7H3BrF4
Molecular Weight	243.00 g/mol
Synonyms	1-Bromo-2-fluoro-5-(trifluoromethyl)benzene; 3-Bromo-4-fluoro-α,α,α-trifluorotoluene; 2-Fluoro-5-(trifluoromethyl)bromobenzene; 3-Bromo-4-fluoro-α,α,α-trifluoromethylbenzene; 3-Bromo-4-fluorobenzylidene trifluoride; 3-Bromo-4-fluoro-(trifluoromethyl)benzene; α,α,α-Trifluoro-3-bromo-4-fluorotoluene
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Fluorobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly closed to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Purity (HPLC)	≥ 97.5%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.