Description

N,n-Dimethyl-9Alpha, 11Alpha, 15S-Trihydroxy-Prosta-5Z, 13E-Dien-1-Amide is a high-purity synthetic prostaglandin derivative, a critical intermediate in advanced pharmaceutical research and development. Its precise stereochemistry and functional groups make it an essential building block for creating novel therapeutic agents targeting inflammation, pain, and cardiovascular function. This compound is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing next-generation drugs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of advanced prostaglandin-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and tool compound in studies of prostaglandin receptors, signal transduction pathways, and inflammatory mediators.
• Drug Discovery: Serves as a core scaffold for medicinal chemistry programs aimed at developing new anti-inflammatory, analgesic, or vasoactive agents.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses requiring high stereochemical control for the production of complex bioactive molecules.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.

Basic Information

Product Name	N,n-Dimethyl-9Alpha, 11Alpha, 15S-Trihydroxy-Prosta-5Z, 13E-Dien-1-Amide
CAS No.	68192-15-4
Molecular Formula	C23H39NO4
Molecular Weight	393.57 g/mol
Synonyms	9α,11α,15S-Trihydroxy-prosta-5Z,13E-dien-1-oic acid, N,N-dimethylamide; N,N-Dimethyl-9α,11α,15S-trihydroxy-prosta-5Z,13E-dien-1-amide; Prostaglandin D2 N,N-dimethylamide derivative; PGD2 dimethylamide; (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dien-1-oic acid dimethylamide
EINECS	Contact for details

Quality Control

Our N,n-Dimethyl-9Alpha, 11Alpha, 15S-Trihydroxy-Prosta-5Z, 13E-Dien-1-Amide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. The material is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.