Description

2-Acetamido-3,5-Dimethoxybenzenesulphonyl Chloride is a specialized aromatic sulphonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its dual functionality, acting as a reactive electrophile for sulfonamide bond formation and offering sites for further modification via its acetamido and methoxy groups. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including potential enzyme inhibitors and receptor antagonists.
• Agrochemical Research: Used in developing new herbicides, fungicides, and plant growth regulators that utilize sulfonamide chemistry.
• Dye and Pigment Synthesis: Serves as an intermediate for creating specialized sulfonated dyes and colorants.
• Polymer Chemistry: Can be incorporated as a monomer or cross-linking agent to introduce sulfonyl chloride functionality into polymers.
• Chemical Biology Probes: Utilized in the design of activity-based probes and affinity labels for studying protein function.
• Custom Synthesis & Contract Manufacturing: A high-value intermediate for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-Acetamido-3,5-Dimethoxybenzenesulphonyl Chloride
CAS No.	68016-04-6
Molecular Formula	C10H12ClNO5S
Molecular Weight	293.72 g/mol
Synonyms	2-Acetamido-3,5-dimethoxybenzenesulfonyl chloride; 3,5-Dimethoxy-2-acetamidobenzenesulfonyl chloride; N-[2-(Chlorosulfonyl)-3,5-dimethoxyphenyl]acetamide; 2-Acetylamino-3,5-dimethoxybenzenesulfonyl chloride; Acetamide, N-[2-(chlorosulfonyl)-3,5-dimethoxyphenyl]-; 68016-04-6; Benzenesulfonyl chloride, 2-acetamido-3,5-dimethoxy-
EINECS	Contact for details

Quality Control

Our 2-Acetamido-3,5-Dimethoxybenzenesulphonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.