Description

11-Dehydro Thromboxane B2 is a stable metabolite of thromboxane A2, a key eicosanoid involved in platelet aggregation and vasoconstriction. This compound serves as a critical biomarker and reference standard for research into cardiovascular diseases, inflammation, and related metabolic pathways. It is essential for pharmaceutical R&D, clinical diagnostics, and academic laboratories focused on eicosanoid biology and drug discovery.

Application

• Biomarker Analysis: Quantitative measurement in biological fluids (e.g., urine, plasma) for clinical research on thrombosis, atherosclerosis, and inflammatory conditions.
• Pharmaceutical Reference Standard: Used in the development, validation, and quality control of assays for drug candidates targeting the thromboxane pathway.
• Metabolic Pathway Research: Investigation of arachidonic acid metabolism and the role of thromboxanes in cellular signaling and disease mechanisms.
• Diagnostic Kit Development: A key component in the manufacture of ELISA and other immunoassay kits for cardiovascular risk assessment.
• Academic & Preclinical Studies: Fundamental research in biochemistry, pharmacology, and physiology to understand eicosanoid function.

Basic Information

Product Name	11-Dehydro Thromboxane B2
CAS No.	67910-12-7
Molecular Formula	C₂₀H₃₂O₆
Molecular Weight	368.47 g/mol
Synonyms	11-Dehydro-TXB2; 11-Dehydrothromboxane B2; DH-TXB2; 11-Dehydro-TXB₂; Thromboxane B2 Metabolite II; 9,11-Dideoxy-9α,11α-epoxymethano-15S-hydroxy-13E-prostenoic acid; 11-Dehydro-thromboxane B2
EINECS	Contact for details

Quality Control

Our 11-Dehydro Thromboxane B2 is produced under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and diagnostic applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in ethanol, methanol; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.