Description

6,9-Dioxo-11Alpha,15S-Dihydroxy-Prost-13E-En-1-Oic Acid is a high-purity synthetic prostaglandin derivative, a key intermediate in advanced pharmaceutical research and development. This compound is valued for its precise stereochemistry and structural integrity, which are critical for producing active pharmaceutical ingredients (APIs) with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical manufacturers specializing in the synthesis of prostaglandin-based therapeutics, including treatments for ocular hypertension, cardiovascular conditions, and inflammatory disorders.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of prostaglandin analogs and related therapeutic agents.
• Ophthalmic Drug Development: Used in research and production of medications for glaucoma and ocular hypertension.
• Cardiovascular Research: Serves as a precursor in studies targeting vasodilation and platelet aggregation.
• Biochemical Research: Employed as a standard or reagent in studies of eicosanoid pathways and receptor binding assays.
• Process Development: Used for scaling up and optimizing synthetic routes for prostaglandin-based APIs under cGMP conditions.

Basic Information

Product Name	6,9-Dioxo-11Alpha,15S-Dihydroxy-Prost-13E-En-1-Oic Acid
CAS No.	67786-53-2
Molecular Formula	C₂₀H₃₀O₆
Molecular Weight	366.45 g/mol
Synonyms	11α,15S-Dihydroxy-6,9-dioxoprost-13-en-1-oic Acid; 6,9-Diketo-PGF1α; 6,9-Dioxo-PGF1α; Prostaglandin F1α 6,9-dione; Travoprost Impurity; Travoprost Related Compound; 6,9-Diketo-11α,15-dihydroxy-prost-13-en-1-oic Acid; 6,9-Dioxo-11α,15-dihydroxy-prost-13E-en-1-oic Acid
EINECS	Contact for details

Quality Control

Our 6,9-Dioxo-11Alpha,15S-Dihydroxy-Prost-13E-En-1-Oic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and conformity to stringent specifications. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, supporting compliance with research and cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature of 15-25°C (59-77°F) to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.