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11-Fluoro-11-Deoxyprostaglandin F2Alpha CAS NO 67719-33-9


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CAS No.:67719-33-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

11-Fluoro-11-Deoxyprostaglandin F2Alpha is a fluorinated analog of prostaglandin F2α, a key bioactive lipid mediator. This compound is valued for its enhanced metabolic stability and targeted biological activity compared to its non-fluorinated counterpart, making it a critical tool in pharmacological research and development. It is primarily utilized by researchers and developers in the pharmaceutical and life sciences industries for investigating prostaglandin receptor function and developing novel therapeutic agents.

Application

  • Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel therapeutics targeting inflammation, ocular pressure, and reproductive health.
  • Biochemical Research: Used as a potent and selective agonist for studying FP prostaglandin receptor signaling pathways and their physiological roles in cellular models.
  • Metabolic Studies: Employed to investigate the structure-activity relationships (SAR) of prostaglandin analogs, with the fluorine substitution providing insights into metabolic stability and potency.
  • Veterinary Medicine Development: Explored for applications in animal health, particularly in areas of luteolysis and reproductive cycle management.
  • High-Purity Analytical Standards: Supplied as a certified reference material (CRM) for the accurate quantification and identification of prostaglandin-related compounds in complex matrices using HPLC and LC-MS.

Basic Information

Product Name 11-Fluoro-11-Deoxyprostaglandin F2Alpha
CAS No. 67719-33-9
Molecular Formula C₂₀H₃₃FO₅
Molecular Weight 372.47 g/mol
Synonyms 11-Fluoro-11-deoxy-PGF2α; Fluprostenol Impurity; 9α,11α,15S-Trihydroxy-11-fluoro-5Z,13E-prostadienoic Acid; 11-F-PGF2α; 11-Fluoro-prostaglandin F2α; 11-Fluoro-PGF2α; 11-F-dPGF2α; Fluprostenol Related Compound A
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Quality Control

Our 11-Fluoro-11-Deoxyprostaglandin F2Alpha is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. For long-term storage, keep desiccated.

Specification

Item Specification
Appearance White to off-white solid
Identification (HPLC) Conforms to reference standard
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Water Content (KF) ≤ 0.5%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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