Description

Amastatin CAS NO 67655-94-1 is a potent and selective aminopeptidase inhibitor, specifically targeting enzymes like aminopeptidase A and leucine aminopeptidase. This compound is a critical biochemical tool for researchers studying proteolytic pathways, signal transduction, and the role of aminopeptidases in various physiological and pathological processes. It is essential for pharmaceutical R&D, academic research in biochemistry and cell biology, and the development of diagnostic assays.

Application

• Biochemical Research: Used as a specific inhibitor to study the function and mechanism of aminopeptidases in enzymatic assays.
• Pharmaceutical Development: Serves as a lead compound or pharmacological tool in drug discovery programs targeting conditions like hypertension, cancer, and inflammatory diseases.
• Cell Biology Studies: Employed to investigate the role of peptide metabolism in cellular processes, including antigen presentation and neuropeptide regulation.
• Diagnostic Reagent Manufacturing: A key component in the formulation of enzyme inhibitor kits for clinical and research diagnostics.
• Neuroscience Research: Utilized to explore the degradation of neuropeptides and its impact on neurological function and behavior.
• Academic & Industrial R&D: A standard reagent in laboratories for fundamental research on proteolysis and peptide hormone regulation.

Basic Information

Product Name	Amastatin
CAS No.	67655-94-1
Molecular Formula	C₂₀H₃₂N₄O₆
Molecular Weight	424.49 g/mol
Synonyms	[(2S,3R)-3-Amino-2-hydroxy-4-methylpentanoyl]-L-valyl-L-valyl-L-aspartic acid; Amastatin Hydrochloride; NSC 326322; Aminopeptidase A Inhibitor; L-Valyl-L-valyl-L-aspartyl-(2S,3R)-3-amino-2-hydroxy-4-methylpentanoic acid
EINECS	Contact for details

Quality Control

Every batch of Amastatin is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and potency, meeting the high standards required for research and development. A Certificate of Analysis (COA) detailing specifications such as HPLC purity, chiral purity, and water content is supplied with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to warm to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC & MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines
Biological Activity (IC₅₀)	Provided on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.