Description

4-Fluoro-3-(trifluoromethyl)benzaldehyde is a versatile fluorinated aromatic aldehyde building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both fluorine and a trifluoromethyl group, imparts unique electronic and steric properties that are highly valuable for modulating the activity and properties of target molecules. This compound is essential for research and development chemists and process engineers working in the pharmaceutical, agrochemical, and materials science industries, where it serves as a key intermediate for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity, metabolic stability, and lipophilicity.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials, improving thermal stability, optical properties, and dielectric anisotropy.
• Polymer & Resin Modifier: Incorporated into specialty polymers to enhance chemical resistance, thermal stability, and surface properties for high-performance coatings and engineering plastics.
• Organic Synthesis & Catalysis: A valuable substrate in cross-coupling reactions, nucleophilic additions, and as a ligand precursor in organometallic chemistry and catalysis research.
• Dye & Pigment Intermediate: Employed in the synthesis of advanced fluorinated dyes and pigments with superior lightfastness and color properties.

Basic Information

Product Name	4-Fluoro-3-(trifluoromethyl)benzaldehyde
CAS No.	67515-60-0
Molecular Formula	C8H4F4O
Molecular Weight	192.11 g/mol
Synonyms	4-Fluoro-3-(trifluoromethyl)benzaldehyde; 3-(Trifluoromethyl)-4-fluorobenzaldehyde; 4-Fluoro-alpha,alpha,α-trifluoro-m-tolualdehyde; 4-Fluoro-3-trifluoromethylbenzaldehyde; Benzaldehyde, 4-fluoro-3-(trifluoromethyl)-; m-Tolualdehyde, 4-fluoro-alpha,alpha,α-trifluoro-
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-(trifluoromethyl)benzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency meet the high standards required for industrial and research applications. Certificates of Analysis (COA) with detailed specifications are available for each lot upon request, providing full traceability and compliance data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended long-term storage temperature is between 2°C and 8°C. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.