Description

3,12-Dihydroxy-7-Oxocholanoyltaurine is a chemically modified bile acid derivative, specifically a taurine conjugate. This compound is of significant interest in biochemical and pharmaceutical research due to its role as a potential intermediate or reference standard in the study of bile acid metabolism and signaling pathways. It is primarily utilized by research institutions and pharmaceutical development companies focused on hepatology, gastroenterology, and metabolic disease research.

Application

• Biochemical Research: Used as a critical intermediate or reference standard in studies investigating bile acid synthesis, conjugation, and transport mechanisms.
• Pharmaceutical Development: Serves as a key starting material or analytical standard in the research and development of novel therapeutics targeting liver and metabolic disorders.
• Metabolic Pathway Analysis: Employed in in vitro and in vivo studies to elucidate the complex pathways of bile acid metabolism and their physiological impacts.
• Analytical Chemistry: Functions as a high-purity calibration standard for analytical methods such as HPLC and LC-MS in bioanalytical laboratories.
• Enzyme Substrate Studies: Utilized as a specific substrate for studying the activity of enzymes involved in bile acid modification, such as hydroxysteroid dehydrogenases.

Basic Information

Product Name	3,12-Dihydroxy-7-Oxocholanoyltaurine
CAS No.	67460-69-9
Molecular Formula	C₂₆H₄₃NO₈S
Molecular Weight	529.69 g/mol
Synonyms	7-Oxo-3,12-dihydroxycholanoyltaurine; 7-Ketolithocholyltaurine; Tauro-7-ketolithocholic acid; 3α,12α-Dihydroxy-7-oxo-5β-cholan-24-oyltaurine; N-(3α,12α-Dihydroxy-7-oxo-5β-cholan-24-oyl)taurine; 7-Keto-LCA taurine conjugate
EINECS	Contact for details

Quality Control

Our 3,12-Dihydroxy-7-Oxocholanoyltaurine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.