Description

19-Hydroxyprostaglandin B2 is a specialized prostaglandin derivative and a key metabolite in the arachidonic acid cascade. This compound is of significant interest in biochemical and pharmacological research for its role as a precursor and biomarker in studies of prostaglandin metabolism and oxidative stress pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers focused on inflammation, cardiovascular function, and lipid mediator research.

Application

• Biochemical Research: Used as a reference standard and analytical tool in studies of prostaglandin biosynthesis, metabolism, and degradation pathways.
• Pharmaceutical Development: Serves as a critical intermediate or biomarker in the research and development of novel anti-inflammatory and cardiovascular therapeutics.
• Diagnostic Assays: Employed as a calibrant or control in the development of immunoassays and LC-MS/MS methods for quantifying prostaglandin metabolites in biological samples.
• Metabolomics Studies: A valuable analyte in lipidomics and metabolomics research to understand the role of oxylipins in disease states and physiological responses.
• Academic Research: Utilized in university and institutional labs for fundamental investigations into eicosanoid biology, oxidative stress, and cell signaling mechanisms.

Basic Information

Product Name	19-Hydroxyprostaglandin B2
CAS No.	67392-20-5
Molecular Formula	C20H32O6
Molecular Weight	368.47 g/mol
Synonyms	19-Hydroxy PGB2; 19-OH-PGB2; (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-1-octen-1-yl]cyclopentyl]-5-heptenoic Acid; 19-Hydroxy-prostaglandin B2; Prostaglandin B2, 19-hydroxy-; 19-Hydroxy PGB₂
EINECS	Contact for details

Quality Control

Our 19-Hydroxyprostaglandin B2 is produced under strict quality management protocols. Each batch is characterized and tested using advanced analytical techniques including HPLC, MS, and NMR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data, supporting its use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. For long-term storage, solutions should be prepared in appropriate anhydrous solvents and kept at -80°C. Allow the sealed vial to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in ethanol, DMSO; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.