Description

(5Z,13E,15R)-15-Hydroxy-16-Methyl-9-Oxoprosta-5,13-Dien-1-Oic Acid is a high-purity prostaglandin analog, a key intermediate in advanced pharmaceutical synthesis. This compound matters for its precise stereochemistry and functional groups, which are critical for developing targeted therapeutic agents. It is primarily needed by research institutions and pharmaceutical manufacturers focused on developing novel drugs in areas such as ophthalmology, cardiovascular research, and inflammation control.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel prostaglandin-based therapeutics.
• Ophthalmic Drug Research: Used in the development of next-generation treatments for glaucoma and ocular hypertension.
• Biochemical Research: Acts as a reference standard and probe in studies of prostaglandin receptors and signaling pathways.
• Cardiovascular Research: Employed in the investigation of vascular tone regulation and related pharmacological mechanisms.
• Process Development: Utilized in scaling up and optimizing synthetic routes for prostaglandin analogs under cGMP conditions.

Basic Information

Product Name	(5Z,13E,15R)-15-Hydroxy-16-Methyl-9-Oxoprosta-5,13-Dien-1-Oic Acid
CAS No.	67314-69-6
Molecular Formula	C21H32O5
Molecular Weight	364.48 g/mol
Synonyms	16-Methyl PGF2α; 16-Methyl Prostaglandin F2α; 15(R)-16-Methyl-9-oxoprosta-5,13-dien-1-oic acid; 15-Hydroxy-16-methyl-9-oxoprosta-5,13-dien-1-oic acid; 16-Me-PGF2α; 16-Methyl-prostaglandin F2α; 9-Oxo-16-methyl-prostaglandin F2α; Prosta-5,13-dien-1-oic acid derivative
EINECS	Contact for details

Quality Control

Our (5Z,13E,15R)-15-Hydroxy-16-Methyl-9-Oxoprosta-5,13-Dien-1-Oic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. For long-term storage, keep the primary container sealed within a secondary, light-proof container. Allow the product to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (15R)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.