Description

1-[4-(Trifluoromethyl)Phenyl]Propan-1-Ol is a versatile fluorinated aromatic alcohol, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in the unique combination of the trifluoromethyl group's lipophilicity and metabolic stability with the reactivity of a secondary alcohol, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key chiral precursor for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Used in the development of fluorinated components for electronic displays and organic light-emitting diodes due to its stable aromatic structure.
• Advanced Polymer Chemistry: Monomer or modifier for introducing fluorine into polymers to improve chemical resistance, thermal stability, and surface properties.
• Asymmetric Catalysis & Ligand Design: Serves as a starting material for synthesizing chiral ligands and auxiliaries used in enantioselective catalytic processes.
• Organic Synthesis & Research: A valuable reagent for academic and industrial R&D exploring new fluorination methodologies and structure-activity relationships.

Basic Information

Product Name	1-[4-(Trifluoromethyl)Phenyl]Propan-1-Ol
CAS No.	67081-98-5
Molecular Formula	C10H11F3O
Molecular Weight	204.19 g/mol
Synonyms	1-(4-(Trifluoromethyl)phenyl)propan-1-ol; α-Ethyl-4-(trifluoromethyl)benzenemethanol; 3-[4-(Trifluoromethyl)phenyl]propan-1-ol (common misnomer); 4-(Trifluoromethyl)phenyl ethyl carbinol; 1-(4-Trifluoromethylphenyl)-1-propanol; (RS)-1-[4-(Trifluoromethyl)phenyl]propan-1-ol; (±)-1-[4-(Trifluoromethyl)phenyl]propan-1-ol; Benzenemethanol, α-ethyl-4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our production of 1-[4-(Trifluoromethyl)Phenyl]Propan-1-Ol adheres to stringent quality management protocols to ensure batch-to-batch consistency and purity for sensitive applications. All material is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We operate under a quality system aligned with ISO 9001 standards, and our processes are designed to meet the exacting requirements of pharmaceutical (ICH Q7) and advanced material synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is compatible with fluoride/strong alkali chemical properties; ensure segregation from incompatible materials. Keep the container tightly sealed when not in use to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.