Description

Globomycin CAS NO 67076-74-8 is a specialized cyclic lipopeptide antibiotic that acts as a potent and selective inhibitor of the bacterial signal peptidase II (LspA). This compound is a critical research tool for studying bacterial lipoprotein biosynthesis and outer membrane assembly. It is primarily utilized by pharmaceutical researchers, microbiologists, and biochemists in the fields of antibiotic discovery, bacterial physiology, and novel antimicrobial mechanism of action studies.

Application

• Antibiotic Research & Development: Serves as a key reference standard and probe compound for investigating novel antibacterial targets, particularly in Gram-negative bacteria.
• Microbial Physiology Studies: Used to elucidate the pathways and functions of bacterial lipoprotein processing and transport, aiding in fundamental biological research.
• Mechanism of Action (MoA) Analysis: Essential for validating and characterizing the inhibitory activity against signal peptidase II in biochemical and whole-cell assays.
• High-Throughput Screening (HTS): Employed as a control compound in screening campaigns to identify new antimicrobial agents with similar or synergistic modes of action.
• Academic & Institutional Research: Supports university and government lab projects focused on bacterial pathogenesis, membrane biogenesis, and drug resistance.

Basic Information

Product Name	Globomycin
CAS No.	67076-74-8
Molecular Formula	C45H73N7O10
Molecular Weight	872.1 g/mol
Synonyms	Globomycin; SF-1902 A5; Antibiotic SF-1902; LspA Inhibitor; Signal Peptidase II Inhibitor; Cyclic Lipopeptide Antibiotic; (3S,6S,9S,12S,15S,18S,21S,24S,27S,33S)-33-[(2R)-2-Hydroxyhexadecanoyl]-3,6,9,12,15,18,21,24,27-nonaaza-2,5,8,11,14,17,20,23,26-nonaoxotriacontan-1-ol
EINECS	Contact for details

Quality Control

Our Globomycin is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and potency. We adhere to relevant standards for research-grade biochemicals, ensuring reliable and reproducible performance in your experiments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Biological Activity (MIC)	Reported

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.