Description

β-Chlornaltrexamine 2Hcl is a high-purity, research-grade chemical compound, specifically the dihydrochloride salt of a potent and selective opioid receptor antagonist. This compound is of significant value for advanced pharmacological and neurochemical research, enabling precise studies on opioid receptor function and signaling pathways. It is primarily required by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on neuroscience, pain management, and addiction research.

Application

• Pharmacological Research: As a key tool compound for in vitro and ex vivo studies targeting opioid receptors (mu, delta, kappa).
• Neurochemical Studies: Investigation of opioid receptor-mediated signaling cascades and neuronal communication.
• Drug Discovery Programs: Used in high-throughput screening (HTS) and lead optimization for developing novel analgesics or treatments for substance use disorders.
• Biochemical Assay Development: Serves as a reference standard or competitive ligand in receptor binding assays and functional tests.
• Academic Neuroscience Research: Fundamental research into the role of opioid systems in pain, reward, and behavior.

Basic Information

Product Name	β-Chlornaltrexamine 2Hcl
CAS No.	67025-98-3
Molecular Formula	C23H31Cl2N3O5 • 2HCl
Molecular Weight	Approx. 569.3 g/mol (Contact for exact details)
Synonyms	β-Chlornaltrexamine Dihydrochloride; β-CNA 2HCl; 6β,14-Epoxy-7α,8α-dihydro-17-(cyclopropylmethyl)-4,5α-epoxy-3-hydroxy-6β-methoxymorphinan-7,8-diol Dihydrochloride; (5α,7α,8β)-17-(Cyclopropylmethyl)-4,5-epoxy-6-methoxy-3,14-dihydroxymorphinan-7,8-diol Dihydrochloride; β-CNA; Chlornaltrexamine β-isomer 2HCl
EINECS	Contact for details

Quality Control

Our β-Chlornaltrexamine 2Hcl is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is analyzed using validated methods, including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your research integrity and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.