Description

2-Bromo-3,4,5,6-Tetrafluorobenzotrifluoride is a highly fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the unique combination of bromine and fluorine substituents, which make it a versatile precursor for introducing perfluorinated aryl groups into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors, particularly for developing novel active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, leveraging fluorine's ability to enhance metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Synthesis: Used in creating advanced, high-performance herbicides, fungicides, and insecticides where fluorinated aromatic rings improve efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a critical building block for fluorinated components in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modification: Incorporated into specialty polymers to impart unique properties such as chemical resistance, thermal stability, and low surface energy.
• Cross-Coupling Reactions: The bromine atom is an excellent handle for palladium-catalyzed reactions (e.g., Suzuki, Stille, Negishi couplings) to construct complex fluorinated architectures.
• Fluorinated Surfactant & Coating Precursor: Used in the synthesis of surfactants and surface treatment agents that require oil- and water-repellent characteristics.

Basic Information

Product Name	2-Bromo-3,4,5,6-Tetrafluorobenzotrifluoride
CAS No.	66820-64-2
Molecular Formula	C7BrF7
Molecular Weight	288.97 g/mol
Synonyms	1-Bromo-2,3,4,5-tetrafluoro-6-(trifluoromethyl)benzene; Benzene, 1-bromo-2,3,4,5-tetrafluoro-6-(trifluoromethyl)-; 2-Bromo-α,α,α,3,4,5,6-heptafluorotoluene; Perfluorobenzyl Bromide, Tetrafluoro-substituted; 2-Bromoheptafluorotoluene; 3,4,5,6-Tetrafluoro-2-bromobenzotrifluoride
EINECS	Contact for details

Quality Control

Our 2-Bromo-3,4,5,6-Tetrafluorobenzotrifluoride is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ISO standards for reliable integration into regulated synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (at 20°C)	~1.9 g/mL
Refractive Index (n20D)	~1.40

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.