Description

17-Debromo-29-De(1-Hydroxyethyl)-29-(Hydroxymethyl)Aplysiatoxin is a structurally defined derivative of the natural product aplysiatoxin, offering a valuable tool for biochemical and pharmacological research. This compound is of significant interest for its role in studying protein kinase C (PKC) signaling pathways and related biological mechanisms. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in cancer research, neurobiology, and inflammatory disease studies.

Application

• Biochemical Research: As a reference standard and probe for investigating the structure-activity relationships of aplysiatoxin analogs.
• Pharmacology Studies: Used in in vitro and cellular assays to study modulation of Protein Kinase C (PKC) isoforms.
• Drug Discovery: Serves as a key intermediate or molecular scaffold in the synthesis of novel therapeutic agents targeting PKC.
• Toxicology Research: Employed to understand the mechanisms of tumor promotion and inflammation associated with natural toxin derivatives.
• Academic Research: Utilized in university and institutional labs for fundamental studies in chemical biology and signal transduction.

Basic Information

Product Name	17-Debromo-29-De(1-Hydroxyethyl)-29-(Hydroxymethyl)Aplysiatoxin
CAS No.	66671-95-2
Molecular Formula	C32H48O9
Molecular Weight	576.73 g/mol
Synonyms	29-De(1-Hydroxyethyl)-29-(hydroxymethyl)-17-debromoaplysiatoxin; Debromo-dehydroxyethyl-hydroxymethylaplysiatoxin; Aplysiatoxin derivative; PKC modulator derivative; 17-Debromo-29-de-O-(1-hydroxyethyl)-29-(hydroxymethyl)aplysiatoxin
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research chemicals. Each batch is characterized using advanced analytical techniques to confirm identity and purity. Certificates of Analysis (COA) detailing purity, analytical methods (e.g., HPLC, NMR), and results are available upon request to support your research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. Allow the container to reach room temperature before opening to minimize moisture condensation. Store away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.