Description

2-Oxo-1,2,3,4-Tetrahydroquinoline-6-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to act as a versatile electrophile for introducing the sulfonamide moiety, a key functional group in numerous bioactive molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel drug candidates and active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing sulfonamide groups for therapeutic applications.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the sulfonamide functionality imparts specific biological activity.
• Chemical Research & Development: Employed as a versatile reagent in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of specialized dyes and pigments requiring sulfonyl chloride chemistry.
• Material Science: Potential use in the synthesis of functional polymers and advanced materials with specific surface properties.

Basic Information

Item	Detail
Product Name	2-Oxo-1,2,3,4-Tetrahydroquinoline-6-Sulfonyl Chloride
CAS No.	66657-42-9
Molecular Formula	C9H8ClNO3S
Molecular Weight	245.68 g/mol
Synonyms	6-Quinolinesulfonyl chloride, 1,2,3,4-tetrahydro-2-oxo-; Tetrahydro-2-oxoquinoline-6-sulfonyl chloride; 1,2,3,4-Tetrahydro-2-oxoquinoline-6-sulfonyl chloride; 2-Oxo-1,2,3,4-tetrahydroquinoline-6-sulfonyl chloride; 6-Sulfonylchloride-2-oxo-1,2,3,4-tetrahydroquinoline; Quinoline-6-sulfonyl chloride, 1,2,3,4-tetrahydro-2-oxo-; 2-Oxo-1,2,3,4-tetrahydro-6-quinolinesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Oxo-1,2,3,4-Tetrahydroquinoline-6-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.