Description

Fosmidomycin, Sodium Salt is a potent and specific inhibitor of the non-mevalonate pathway enzyme 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR). This compound matters as a critical research tool for studying isoprenoid biosynthesis in bacteria and the malaria parasite *Plasmodium falciparum*, offering a unique mechanism of action. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on antimicrobial discovery and metabolic pathway analysis. The product is supplied as a high-purity biochemical reagent suitable for in vitro studies.

Application

• Antimicrobial Research: Investigation of novel antibacterial agents targeting the non-mevalonate (MEP) pathway in Gram-negative and Gram-positive bacteria.
• Antimalarial Studies: Essential tool for probing isoprenoid biosynthesis in *Plasmodium falciparum* and validating DXR as a drug target.
• Biochemical Pathway Analysis: Used to inhibit DXR in cell-based and cell-free systems to study the downstream effects on isoprenoid and sterol production.
• Enzyme Inhibition Assays: Serves as a reference standard in high-throughput screening (HTS) campaigns for DXR inhibitor discovery.
• Plant Biology Research: Applied in studies of the plastidial MEP pathway in plants and algae.
• Microbial Physiology: Used to elucidate the role of isoprenoids in bacterial cell wall biosynthesis and growth.

Basic Information

Product Name	Fosmidomycin, Sodium Salt
CAS No.	66508-37-0
Molecular Formula	C4H8NNaO7P
Molecular Weight	236.07 g/mol
Synonyms	FR-31564; FR31564; Sodium Fosmidomycin; (3-Formamido-2-hydroxypropyl)phosphonic Acid Monosodium Salt; (3-(Formylamino)-2-hydroxypropyl)phosphonic Acid Sodium Salt; Antibiotic FR-31564; Phosphonic acid, P-[(3-formylamino)-2-hydroxypropyl]-, monosodium salt
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized to confirm identity, purity, and potency, making it suitable for critical research applications. Certificates of Analysis (COA) detailing specific test results, including assay by HPLC and impurity profiles, are available upon request. We adhere to strict in-house quality protocols to ensure batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥95.0%
Water Content (KF)	≤5.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Bacterial Endotoxins	<1.0 EU/mg (where applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.