Description

2-Methyl-5-(Trifluoromethyl)Bromobenzene is a high-purity, multi-functional aromatic building block essential for advanced organic synthesis. Its unique structure, featuring both a bromine substituent and a trifluoromethyl group, makes it a critical intermediate for introducing specific functionalities into target molecules. This compound is primarily utilized by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of compounds with trifluoromethyl motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for sophisticated ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of specialty monomers for advanced polymers and liquid crystals.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Functional Group Transformation: The bromine atom allows for further functionalization via nucleophilic substitution or metal-halogen exchange.

Basic Information

Product Name	2-Methyl-5-(Trifluoromethyl)Bromobenzene
CAS No.	66417-30-9
Molecular Formula	C8H6BrF3
Molecular Weight	239.04 g/mol
Synonyms	1-Bromo-2-methyl-5-(trifluoromethyl)benzene; 2-Methyl-α,α,α-trifluoro-5-bromotoluene; 5-Bromo-2-methylbenzotrifluoride; 2-Methyl-5-(trifluoromethyl)phenyl bromide; 5-Bromo-α,α,α-trifluoro-o-xylene; 2-Methyl-5-trifluoromethylbromobenzene; 5-Bromo-2-methylbenzyl trifluoride
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-(Trifluoromethyl)Bromobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.