Description

α-Bromo-p-Toluenesulphonyl Chloride is a versatile and highly reactive organosulfur compound, primarily used as a key building block in organic synthesis. Its value lies in its dual functionality, serving as both a sulfonylating agent and an alkylating agent, which enables the efficient construction of complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for the development of active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of sulfonamide-based drugs and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents.
• Dye and Pigment Manufacturing: Serves as a precursor for sulfonated dyes and specialty colorants.
• Polymer Chemistry: Employed in the modification of polymers and the creation of functional materials.
• Chemical Research & Development: A valuable reagent for introducing the tosyl (p-toluenesulfonyl) group and bromoalkyl chains in exploratory synthesis.
• Peptide Chemistry: Can be used for the protection of amino groups or as a coupling reagent in peptide synthesis.

Basic Information

Product Name	α-Bromo-p-Toluenesulphonyl Chloride
CAS No.	66176-39-4
Molecular Formula	C7H6BrClO2S
Molecular Weight	269.54 g/mol
Synonyms	α-Bromo-p-toluenesulfonyl chloride; (Bromomethyl)(4-methylphenyl)sulfonyl chloride; p-Toluenesulfonyl bromide chloride; Tosyl bromide chloride; Bromomethyl tosyl chloride; 4-Methylbenzenesulfonyl bromide chloride; (4-Methylphenyl)sulfonyl(bromomethyl) chloride
EINECS	Contact for details

Quality Control

Our α-Bromo-p-Toluenesulphonyl Chloride is produced under stringent quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.