Description

(Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E)-2-[2-[(3-Trifluoromethylphenoxy)Methyl]-1,3-Dioxolan-2-Yl]Ethenyl]Cyclopentan-1α-Yl]-5-Heptenoic Acid Methyl Ester is a high-purity, complex synthetic intermediate of significant importance in advanced pharmaceutical research and development. This compound serves as a critical building block in the synthesis of prostaglandin analogs and other bioactive molecules, enabling precise control over stereochemistry and functional group presentation. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing novel therapeutics.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of prostaglandin and prostacyclin analogs for therapeutic applications.
• Medicinal Chemistry Research: Used as a sophisticated building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses requiring high stereochemical fidelity and complex molecular architecture.
• Biochemical Research: Potential tool compound for studying prostaglandin receptor interactions and related signaling pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of active pharmaceutical ingredients (APIs) under cGMP.
• Academic Research: Utilized in university and institutional labs for advanced studies in synthetic organic chemistry and pharmacology.

Basic Information

Item	Details
Product Name	(Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E)-2-[2-[(3-Trifluoromethylphenoxy)Methyl]-1,3-Dioxolan-2-Yl]Ethenyl]Cyclopentan-1α-Yl]-5-Heptenoic Acid Methyl Ester
CAS No.	66176-12-3
Molecular Formula	C26H31F3O7
Molecular Weight	512.52 g/mol
Synonyms	Methyl (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-[2-[(3-Trifluoromethylphenoxy)methyl]-1,3-dioxolan-2-yl]prop-1-en-1-yl]cyclopentyl]hept-5-enoate; Prostaglandin F2α Trifluoromethyl Phenoxy Methyl Dioxolane Methyl Ester Analog; 66176-12-3; UNII-7G1J8438WQ; 7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-[2-[(3-Trifluoromethylphenoxy)methyl]-1,3-dioxolan-2-yl]prop-1-en-1-yl]cyclopentyl]-5-heptenoic Acid Methyl Ester; (Z)-Isomer of Latanoprost Related Compound; 7G1J8438WQ
EINECS	Contact for details

Quality Control

Our production of (Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E)-2-[2-[(3-Trifluoromethylphenoxy)Methyl]-1,3-Dioxolan-2-Yl]Ethenyl]Cyclopentan-1α-Yl]-5-Heptenoic Acid Methyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We can supply material compliant with various customer-specific requirements and support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.