Description

(Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E)-2-[2-(2-Phenylethyl)-1,3-Dioxolan-2-Yl]Ethenyl]Cyclopentan-1α-Yl]-5-Heptenoic Acid Methyl Ester is a high-purity, synthetic prostaglandin intermediate of significant commercial and research importance. This compound serves as a critical building block in the synthesis of advanced pharmaceutical agents, particularly those targeting cardiovascular and ocular conditions. It is essential for R&D chemists and process development scientists in the pharmaceutical and fine chemical industries seeking reliable, high-quality intermediates for complex synthesis pathways.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the production of prostaglandin analogs and related therapeutic agents.
• Ophthalmic Drug Synthesis: Used in the research and manufacturing of drugs for glaucoma treatment and other ocular pressures.
• Cardiovascular Research: Serves as a vital intermediate in the development of compounds for cardiovascular disease research.
• Organic Synthesis: A versatile chiral building block for constructing complex molecular architectures in medicinal chemistry.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial production of prostaglandin-based APIs.
• Biochemical Research: Used as a standard or reference material in studies involving eicosanoid pathways and receptor binding.

Basic Information

Item	Detail
Product Name	(Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E)-2-[2-(2-Phenylethyl)-1,3-Dioxolan-2-Yl]Ethenyl]Cyclopentan-1α-Yl]-5-Heptenoic Acid Methyl Ester
CAS No.	66176-09-8
Molecular Formula	C28H38O6
Molecular Weight	470.60 g/mol
Synonyms	Methyl (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E)-3-oxo-4-(3-phenoxypropyl)but-1-en-1-yl]cyclopentyl]hept-5-enoate; Prostaglandin F2α Methyl Ester Intermediate; 9,11,15-Trihydroxy-17-phenyl-18,19,20-trinorprosta-5,13-dien-1-oic Acid Methyl Ester; Latanoprost Intermediate; Travoprost Related Compound; Isopropylidene Prostaglandin F2α Methyl Ester; 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(phenoxy)propyl]-1-buten-1-yl]cyclopentyl]-, methyl ester, (5Z)-
EINECS	Contact for details

Quality Control

Every batch of our (Z)-7-[(1R)-3α,5α-Dihydroxy-2β-[(E)-2-[2-(2-Phenylethyl)-1,3-Dioxolan-2-Yl]Ethenyl]Cyclopentan-1α-Yl]-5-Heptenoic Acid Methyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles by HPLC, NMR, and MS are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.