Description

Clofedanol o-β-D-Glucuronide is a specific glucuronide conjugate of the antitussive agent clofedanol. This compound is of significant value as a key reference standard and metabolite in pharmaceutical research and development. It is primarily needed by analytical laboratories and pharmaceutical companies for method development, pharmacokinetic studies, and quality control of related drug substances and products.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification and quantification of clofedanol metabolites in biological matrices.
• Drug Metabolism & Pharmacokinetics (DMPK): Essential for studying the metabolic pathways, bioavailability, and excretion profiles of clofedanol.
• Analytical Method Development: Serves as a critical standard for developing and validating HPLC, LC-MS, and other chromatographic assays.
• Quality Control & Assurance: Employed in the purity testing and batch release of clofedanol-based pharmaceutical products to ensure consistency and safety.
• Biomedical Research: Utilized in in-vitro and in-vivo studies to understand the pharmacological and toxicological profile of clofedanol glucuronidation.

Basic Information

Product Name	Clofedanol o-β-D-Glucuronide
CAS No.	66171-85-5
Molecular Formula	C23H30ClNO8
Molecular Weight	484.94 g/mol
Synonyms	Clofedanol Glucuronide; Clofedanol O-β-D-Glucopyranosiduronic Acid; 2-[2-Chloro-α-[(2-dimethylaminoethyl)phenylbenzyl]oxy]-β-D-glucopyranuronic Acid; Clofedanol Metabolite; Chlophedianol Glucuronide; U-25179E Glucuronide; o-Glucuronide of Clofedanol
EINECS	Contact for details

Quality Control

Our Clofedanol o-β-D-Glucuronide is produced and handled under strict quality management protocols. Each batch is subjected to comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by HPLC, to ensure it meets the high standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.