Description

Saframycin D CAS NO 66082-30-2 is a potent quinone-containing antibiotic compound belonging to the saframycin family. It is valued in research for its significant biological activity, particularly its ability to inhibit DNA synthesis and function as an antitumor agent. This makes it a critical material for pharmaceutical R&D, specifically in the development of novel chemotherapeutic agents and in biochemical studies targeting cancer cell mechanisms.

Application

• Anticancer Research: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel chemotherapeutic drugs.
• Biochemical Mechanism Studies: Used to study DNA alkylation, cross-linking, and the inhibition of topoisomerases in cellular models.
• Microbiology Research: Investigated for its potent antibacterial activity against Gram-positive bacteria in academic and industrial laboratories.
• Pharmaceutical Development: Employed as a lead compound for structural modification and synthesis of analogs with improved efficacy and reduced toxicity profiles.

Basic Information

Product Name	Saframycin D
CAS No.	66082-30-2
Molecular Formula	C₂₈H₃₀N₄O₇
Molecular Weight	534.56 g/mol
Synonyms	Saframycin D; Antibiotic A-130; NSC 339641; 1H-1,3-Benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridine-6,8-diol, 2,3,10,11-tetrahydro-4,9-dimethoxy-2,11-dimethyl-, (2S,11S)-; (2S,11S)-2,3,10,11-Tetrahydro-4,9-dimethoxy-2,11-dimethyl-1H-1,3-benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridine-6,8-diol
EINECS	Contact for details

Quality Control

Our Saframycin D is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to prevent oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	Yellow to orange-brown powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.