Description

3-(2-Methyl-1,3-thiazol-4-yl)benzenesulfonyl chloride is a high-purity sulfonyl chloride derivative, a critical building block in modern organic synthesis. Its primary value lies in its role as a versatile electrophilic reagent for introducing the sulfonamide functional group, a key moiety in many active pharmaceutical ingredients. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries engaged in the synthesis of novel heterocyclic compounds and sulfonamide-based molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing sulfonamide groups for therapeutic applications.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the sulfonamide moiety imparts biological activity.
• Chemical Biology & Proteomics: Serves as a reactive handle for labeling, modifying, or inhibiting biological targets in research settings.
• Material Science Research: Employed in the development of advanced polymers and functional materials requiring specific sulfonated components.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke molecules for clients.

Basic Information

Product Name	3-(2-Methyl-1,3-thiazol-4-yl)benzenesulfonyl chloride
CAS No.	66047-75-4
Molecular Formula	C10H8ClNO2S2
Molecular Weight	273.76 g/mol
Synonyms	3-(2-Methyl-4-thiazolyl)benzenesulfonyl chloride; 4-(3-Chlorosulfonylphenyl)-2-methylthiazole; Benzenesulfonyl chloride, 3-(2-methyl-4-thiazolyl)-; 2-Methyl-4-(3-chlorosulfonylphenyl)thiazole; 66047-75-4; 3-(2-Methylthiazol-4-yl)phenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 3-(2-Methyl-1,3-thiazol-4-yl)benzenesulfonyl chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.