Description

Chlordiazepoxide-D5 is a deuterated internal standard of the benzodiazepine drug chlordiazepoxide, specifically designed for analytical applications. This high-purity, isotopically labeled compound is essential for ensuring the accuracy and reliability of quantitative analysis in complex matrices. It is primarily utilized by pharmaceutical R&D laboratories, forensic toxicology units, and contract research organizations (CROs) for method development, validation, and routine drug level monitoring.

Application

• Internal Standard for Liquid Chromatography-Mass Spectrometry (LC-MS/MS) analysis of chlordiazepoxide and its metabolites.
• Quantitative analysis in pharmacokinetic and bioequivalence studies.
• Reference material for forensic and clinical toxicology testing.
• Method development and validation in pharmaceutical quality control laboratories.
• Calibration standard for doping control and sports drug testing programs.
• Research tool in drug metabolism and disposition studies.

Basic Information

Item	Detail
Product Name	Chlordiazepoxide-D5
CAS No.	65891-81-8
Molecular Formula	C16H9D5ClN3O
Molecular Weight	305.78 g/mol
Synonyms	7-Chloro-2-(methylamino)-5-phenyl-3H-1,4-benzodiazepine 4-oxide-d5; Librium-D5; Methaminodiazepoxide-D5; CDP-D5; Chlordiazepoxide (phenyl-d5); Deuterated Chlordiazepoxide; Chlordiazepoxide-d5 (major)
EINECS	Contact for details

Quality Control

Our Chlordiazepoxide-D5 is manufactured under strict quality systems to ensure the highest standards of purity and isotopic enrichment required for analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing chemical purity, isotopic purity (D-enrichment), and identity confirmation. We adhere to relevant guidelines for reference standards to ensure data integrity and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Chemical Purity (by HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.