Description

4-Methyl-3-Nitrobenzotrifluoride is a versatile fluorinated aromatic nitro compound, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity of the nitro and trifluoromethyl groups, enabling precise chemical transformations. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a fluorinated aromatic core for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group often contributes to improved efficacy and environmental profile.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing properties.
• Dye and Pigment Manufacturing: Intermediate for creating complex, high-performance colorants and imaging agents.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Heck) for constructing complex biaryl structures.
• Nucleophilic Aromatic Substitution: The nitro group activates the ring for displacement reactions, facilitating the introduction of various nucleophiles.

Basic Information

Product Name	4-Methyl-3-Nitrobenzotrifluoride
CAS No.	65754-26-9
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	3-Nitro-4-(trifluoromethyl)toluene; 4-(Trifluoromethyl)-3-nitrotoluene; 1-Methyl-2-nitro-5-(trifluoromethyl)benzene; α,α,α-Trifluoro-4-methyl-3-nitrotoluene; 2-Nitro-α,α,α-trifluoro-p-xylene; Benzene, 1-methyl-2-nitro-5-(trifluoromethyl)-; 4-Methyl-3-nitrobenzotrifluoride
EINECS	Contact for details

Quality Control

Our 4-Methyl-3-Nitrobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.