Description

Benzofuran, 3-(Trifluoromethyl)- CAS NO 65715-21-1 is a high-purity fluorinated benzofuran derivative, a versatile and valuable building block in advanced organic synthesis. Its core value lies in the unique combination of the benzofuran scaffold with the electron-withdrawing trifluoromethyl group, enabling precise modulation of electronic and steric properties in target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group improves lipophilicity and biological activity.
• Material Science Research: Serves as a precursor for functionalized organic materials, including organic light-emitting diodes (OLEDs) and liquid crystals.
• Fluorine Chemistry: An important substrate for studying fluorination reactions and creating complex fluorinated aromatic systems.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Benzofuran, 3-(Trifluoromethyl)-
CAS No.	65715-21-1
Molecular Formula	C9H5F3O
Molecular Weight	186.13 g/mol
Synonyms	3-(Trifluoromethyl)benzofuran; 3-Trifluoromethylbenzofuran; 3-Trifluoromethyl-1-benzofuran; 1-Benzofuran, 3-(trifluoromethyl)-; α,α,α-Trifluoro-m-cresol oxide (related); 3-CF3-Benzofuran
EINECS	Contact for details

Quality Control

Our Benzofuran, 3-(Trifluoromethyl)- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.