Description

Quinoline-6-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative of quinoline, serving as a critical building block in advanced organic synthesis. Its primary value lies in its role as a versatile sulfonylation reagent, enabling the introduction of the quinoline-6-sulfonyl moiety to create novel compounds with targeted properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in medicinal chemistry research for creating sulfonamide-based therapeutics.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the quinoline scaffold imparts specific biological activity.
• Material Science Research: Employed in the creation of functionalized polymers and advanced materials requiring sulfonylated quinoline units.
• Dye and Pigment Intermediate: Serves as a precursor in the synthesis of specialized dyes and pigments with enhanced properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and enzyme activity.
• Ligand Synthesis for Catalysis: Acts as a starting material for creating complex ligands used in homogeneous catalysis.

Basic Information

Product Name	Quinoline-6-Sulfonyl Chloride
CAS No.	65433-99-0
Molecular Formula	C9H6ClNO2S
Molecular Weight	227.67 g/mol
Synonyms	6-Quinolinesulfonyl chloride; Quinoline-6-sulfonyl chloride; 6-Chlorosulfonylquinoline; Quinoline-6-sulfonchlorid; 6-Sulfonylchloroquinoline; 6-Quinolinesulphonyl chloride; 65433-99-0; Quinoline-6-SO2Cl
EINECS	Contact for details

Quality Control

Our Quinoline-6-Sulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity determination, to meet the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as identity, purity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.