Description

15-Hydroperoxyprostaglandin E2 is a bioactive lipid mediator derived from arachidonic acid metabolism, specifically a hydroperoxy derivative of Prostaglandin E2. This compound is of significant value as a key intermediate and reference standard in the study of eicosanoid biosynthesis, oxidative stress pathways, and inflammatory responses. It is primarily required by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for advanced biochemical research, drug discovery, and analytical method development.

Application

• Biochemical Research: Used as a critical intermediate and reference standard in studies of prostaglandin and leukotriene biosynthesis pathways.
• Pharmaceutical Development: Serves as a key starting material or analytical standard in the research and development of anti-inflammatory and immunomodulatory drugs.
• Cell Signaling Studies: Employed to investigate the role of lipid peroxidation products in cellular signaling, oxidative stress, and apoptosis.
• Analytical Chemistry: Utilized as a high-purity standard for method validation in HPLC, LC-MS, and other chromatographic techniques for eicosanoid analysis.
• Enzymology: Acts as a substrate for studying the activity and kinetics of enzymes like cyclooxygenases (COX) and lipoxygenases (LOX).
• Academic Research: Essential for university and institutional research projects focused on lipidomics, inflammation biology, and metabolic disorders.

Basic Information

Product Name	15-Hydroperoxyprostaglandin E2
CAS No.	65380-05-4
Molecular Formula	C₂₀H₃₂O₇
Molecular Weight	384.47 g/mol
Synonyms	15(S)-HPETE; 15(S)-Hydroperoxyeicosatetraenoic Acid; 15-HPETE; 15(S)-HPETE; 15-Hydroperoxy-5Z,8Z,11Z,13E-eicosatetraenoic Acid; 15(S)-Hydroperoxy-5,8,11,13-eicosatetraenoic Acid; PGH2 analog; 15-Hydroperoxy-PGE2
EINECS	Contact for details

Quality Control

Our 15-Hydroperoxyprostaglandin E2 is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profiles is supplied with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. Keep away from strong oxidizers and bases.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in ethanol, DMSO; slightly soluble in aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.