Description

Mono-(6-(Triethylenetetraamine)-6-Deoxy)-β-Cyclodextrin is a chemically modified cyclodextrin derivative where a single primary hydroxyl group on the β-cyclodextrin scaffold is replaced by a triethylenetetraamine (TETA) linker. This modification is critical as it introduces multiple amine functionalities, transforming the molecule into a powerful host-guest complexing agent with enhanced binding affinity and selectivity for specific anionic or metal-containing guest molecules. It is primarily sought after by researchers and formulators in the pharmaceutical, diagnostic, and advanced materials sectors who require precise molecular encapsulation, chiral separation, or targeted delivery systems.

Application

• Pharmaceutical Research & Drug Delivery: As a functionalized carrier to improve the solubility, stability, and bioavailability of poorly soluble active pharmaceutical ingredients (APIs).
• Chiral Separation & Analysis: Employed as a chiral selector or stationary phase modifier in capillary electrophoresis (CE) and high-performance liquid chromatography (HPLC) for enantiomeric resolution.
• Catalysis & Supramolecular Chemistry: Serving as a molecular scaffold or ligand to construct enzyme mimics or supramolecular catalysts, leveraging its cavity and amine groups for substrate binding and activation.
• Diagnostic Agent Formulation: Used to complex with contrast agents or fluorescent probes, enhancing their stability and targeting properties for imaging applications.
• Sensor Development: Acting as a recognition element in chemical sensors and biosensors due to its selective binding properties towards specific anions or metal ions.
• Wastewater Treatment & Metal Recovery: Potential application in chelating and removing specific heavy metal ions from industrial effluents.

Basic Information

Product Name	Mono-(6-(Triethylenetetraamine)-6-Deoxy)-β-Cyclodextrin
CAS No.	65294-33-9
Molecular Formula	C48H84N4O34
Molecular Weight	~1261.20 g/mol
Synonyms	6A-Deoxy-6A-(triethylenetetraamino)-β-cyclodextrin; Mono-6-deoxy-6-(triethylenetetraamino)-β-cyclodextrin; β-CD-TETA; 6-Triethylenetetraamino-β-cyclodextrin; 6A-(Triethylenetetraamino)-6A-deoxy-β-cyclodextrin; TETA-β-CD; Amino-functionalized β-cyclodextrin (TETA type); 6-Mono-(triethylenetetraamine)-β-cyclodextrin
EINECS	Contact for details

Quality Control

Our Mono-(6-(Triethylenetetraamine)-6-Deoxy)-β-Cyclodextrin is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (by HPLC/NMR), substitution degree, residual solvent content, and specific rotation. Our quality commitment aligns with cGMP principles for research and pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent absorption of moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC/NMR)	≥ 95.0%
Substitution Degree (DS)	0.9 - 1.1 (per β-CD molecule)
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.